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War and famine are generally associated with the loss of millions of lives. However, the influenza epidemic of 1918 killed more human beings than World War I altogether. One fifth of the world's population was infected by the virus. It killed more people than any other disease on record. The flu not only infected children and the elderly, but also young adults who would typically survive diseases of this kind. The deaths of so many youth contributed to the "Lost Generation" after World War I, resulting in new movements within the 1920s culture. The influenza epidemic has great historical significance, for it was not only a great tragedy, but also resulted in social changes throughout the world.