MyHeritage today announced the MyHeritage DNA Health + Ancestry test, a major expansion of its DNA product line. The following is the announcement:
The new MyHeritage DNA Health + Ancestry test provides comprehensive health reports for conditions affected by genetics including heart disease, breast cancer, type 2 diabetes, and Alzheimer’s disease
Tel Aviv, Israel & Lehi, Utah — MyHeritage, the leading global service for family history and DNA testing, announced today a major expansion of its DNA product line with the launch of the MyHeritage DNA Health + Ancestry test. The test provides a new dimension of genetic insight with comprehensive health reports that can empower future health and lifestyle choices. It is a superset of the current MyHeritage DNA Ancestry-Only test, and includes its pillar features: a percentage breakdown of ethnic origins and matching to relatives through shared DNA. MyHeritage is now the only global consumer DNA company to offer an extensive health and ancestry product in over 40 languages.
The launch of the Health + Ancestry product distinguishes MyHeritage as the only major service that bridges consumers’ past, present, and future: MyHeritage’s integrated suite of products enable users to discover their family history and ethnic origins, find new relatives, and receive valuable insights to help manage choices regarding their health that may impact their future well-being.
“Our Health + Ancestry test is the next step in the evolution of MyHeritage. After 16 years of changing lives for the better through family history research and genetic genealogy, we are excited to expand our mission and try to improve and save lives as well. Our vision is to integrate our successful family history technologies with the new health product in innovative ways that bridge heritage and heredity to deliver deeper insights for our users,” said Gilad Japhet, founder and CEO of MyHeritage. “We are proud to be part of a movement to democratize healthcare globally and make genetic testing accessible to millions of people, and allow them to discover what makes them unique.”
The MyHeritage DNA Health + Ancestry test provides health reports that show users their risk of developing or carrying genetic conditions. Reports include conditions where specific genes contribute to the risk, such as hereditary breast cancer, late-onset Alzheimer’s disease, and late-onset Parkinson’s disease; conditions associated with multiple genes, such as heart disease, and type 2 diabetes; and carrier status reports on conditions that can be passed down from a couple to their children, such as Tay-Sachs disease and cystic fibrosis.
In total, MyHeritage’s Health + Ancestry test covers one of the most extensive ranges of conditions offered by an at-home DNA test: 11 Genetic Risk Reports, including a hereditary breast cancer (BRCA) report that tests 10 pathogenic variants; 3 Polygenic Risk Reports; and 15 Carrier Status Reports.
The World Health Organization identifies cardiovascular disease as the number one cause of death globally. This makes MyHeritage’s unique report for heart disease risk particularly beneficial. This report is based on a cutting-edge method called Polygenic Risk Score that examines hundreds, and in some cases thousands of variants across the entire genome.
In addition to heart disease, the Health + Ancestry product also includes a Polygenic Risk Score for type 2 diabetes, a condition that has significantly increased in prevalence in recent decades and now affects hundreds of millions of people worldwide and 40% of Americans within their lifetime. MyHeritage is also unique in providing a third Polygenic Risk Score for breast cancer, which delivers a risk assessment for breast cancer when none of the BRCA variants that MyHeritage tests for are found. MyHeritage is currently the only major home DNA testing company to offer Polygenic Risk Reports for multiple conditions, and more Polygenic Risk Reports will be added shortly after the product’s initial release. The three initial Polygenic Risk Reports support only populations with European ancestry, but the company has begun conducting research to allow the polygenic reports to cover a broader spectrum of populations in the future.
The new product is based on robust scientific research conducted by the MyHeritage science team led by MyHeritage’s Chief Science Officer, Dr. Yaniv Erlich. It has been in development for two years and leverages the company’s growing expertise in genomics. MyHeritage’s prowess in the field of consumer genetics has led to the growth of its DNA database to 3 million people in under two and a half years. To balance the needs of genetic genealogy and health testing, MyHeritage has custom-designed a new DNA chip using Illumina’s Global Screening Array (GSA). The new chip provides MyHeritage with the flexibility to add reports for more conditions, without the need for users to retest their DNA. Several new health reports are already in the pipeline for release over the coming months following the company’s rigorous validation processes.
MyHeritage DNA Health + Ancestry is a Laboratory Developed Test, processed in a CLIA certified and CAP accredited DNA lab in Texas. The at-home DNA test is an easy and painless cheek swab, and does not require spitting as some other tests do, which makes it more suitable and convenient for all populations, including older people.
Health reports only determine users’ genetic risk for the supported conditions. However, all users are required to complete a personal and family health history questionnaire, to ensure that each user receives the reports appropriate for them. MyHeritage works with PWNHealth, an independent physician network and genetic counseling service, to provide end-to-end physician oversight of the MyHeritage DNA Health + Ancestry test for all U.S. customers, which includes genetic counseling, if appropriate. PWNHealth’s physician oversight and genetic counseling fee is included in the total price.
Privacy is strictly enforced. All health data is protected by state-of-the-art encryption. Health report data is secured using additional password protection and is so secure that even MyHeritage employees cannot access it. MyHeritage has never licensed or sold user data, and has committed to never do so without obtaining explicit user consent. MyHeritage is the only consumer DNA company that has pledged to never sell data to insurance companies. It also applies a strict policy to prohibit use of its DNA services by law enforcement agencies.
The MyHeritage DNA Health + Ancestry kit is available at the price of $199 + shipping. Users who have already purchased a MyHeritage DNA test for ethnicity and genealogy matching can upgrade to receive health reports for $120. To order, visit the MyHeritage DNA website. An annual Health subscription is available as an optional add-on to the new DNA kit, which grants users access to new health reports as they are released. As a special benefit for the launch, the Health subscription is currently offered for free for the first twelve months and users can cancel it anytime.
The new health product is not intended to independently diagnose, prevent, or treat any disease or condition or tell users anything about their current state of health in the absence of medical and clinical information. The product is also not intended for making medical decisions, including prescription or dosing of medications. Users may need to obtain further services from their physician, a genetic counselor, or other healthcare provider, in order to obtain diagnostic results regarding the conditions or diseases indicated within the MyHeritage DNA health reports. The health reports provide genetic risk information based on assessment of specific genetic variants but do not report on users’ entire genetic profile. The health reports do not detect all genetic variants related to a given disease, and the absence of a variant tested does not rule out the presence of other genetic variants that may be related to the disease. For most diseases, currently known genes are only responsible for a portion of the overall risk. Other factors such as environment and lifestyle may affect the risk of developing a given disease and, depending on the condition, may be more relevant predictors. If a user’s data indicate that the user is not at elevated genetic risk for a disease or condition, this should not be interpreted as meaning that the user is safe from developing the disease or condition. The opposite is also true; if a user’s data indicates that the user is at an elevated genetic risk for a disease or condition, it does not mean that the user will definitively develop the disease or condition. Any findings within the health reports should be confirmed and supplemented by additional medical and clinical testing as recommended by the user’s healthcare provider.
MyHeritage DNA Health + Ancestry is available globally except in a few countries that do not allow health-related consumer genetic testing. In the USA, it is available in all states except New York, New Jersey, and Rhode Island, where separate laboratory certifications are required and are currently being pursued. Altogether, MyHeritage DNA Health + Ancestry is now the genetic test for health available in the greatest number of languages and with the widest global reach.